TOXICITY STUDIES OF BOSWELLIA DALZIELII AGAINST CANDIDA AND ASPERGILLUS SPECIES IN KEBBI STATE, NIGERIA

Hauwa’u Bello Abubakar and **Aisha Umar

ABSTRACT

Plant extracts are commonly used as herbs all over the world. The practice, in most underdeveloped countries, is with little or no regulation from constituted authorities. Some of these herbs though, probably effective, may be toxic. Toxicological investigations of these herbs need to be conducted to establish their safety and dosages. In this study, the toxicological examination of a widely used plant for herbs in Sokoto State of Nigeria was conducted. The acute and sub-acute toxicity tests of the methanol leaf extracts of Boswellia Dalziel were performed on experimental rats. Tests were conducted to find derangement in the liver function of animals administered with crude extracts during the acute and sub-chronic toxicity studies. The study showed that the extracts did not create any adverse effects on the tested animals. Both the acute and sub-chronic tests of Boswelliadalzielii methanol extracts produced no harmful effects on the tested animals.